Boston, MA - Charles Lee, PhD, of Brigham and Women’s Hospital’s (BWH) Department of Pathology, and colleagues have generated the first map of the human genome that looks at duplications and deletions of large DNA segments found in healthy individuals, also known as copy number variants (CNVs), some of which are responsible for individual differences in susceptibility to diseases such as AIDS. These findings appear in the November 23, 2006 issue of Nature and are the product of an international research consortium between BWH, Harvard Medical School (HMS), The Hospital for Sick Children in Toronto, Canada, The Wellcome Trust Sanger Institute in Cambridge, England, The University of Tokyo and Affymetrix.
